{"id":9053,"date":"2025-11-12T16:27:42","date_gmt":"2025-11-12T15:27:42","guid":{"rendered":"https:\/\/dev.hifu-prostate.fr\/fr\/?page_id=9053"},"modified":"2025-11-12T16:31:03","modified_gmt":"2025-11-12T15:31:03","slug":"gleason-score-definition-et-explications","status":"publish","type":"page","link":"https:\/\/dev.hifu-prostate.fr\/fr\/en-savoir-plus-sur-le-cancer-de-la-prostate\/gleason-score-definition-et-explications\/","title":{"rendered":"Gleason Score : d\u00e9finition et explications"},"content":{"rendered":"\t\t
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\n \nGleason Score : d\u00e9finition et explications\n<\/strong>\n<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Reconnu comme facteur pronostique majeur du cancer de la prostate, le score de Gleason repr\u00e9sente aujourd\u2019hui une donn\u00e9e essentielle qu\u2019il convient de d\u00e9finir et d\u2019expliquer. Calculer le Gleason score<\/a> permet au corps m\u00e9dical de mesurer l\u2019\u00e9tendue et l\u2019agressivit\u00e9 de la maladie. Le traitement du cancer de la prostate<\/a> \u00e0 proposer est en partie fonction du Gleason score.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Gleason Score : d\u00e9finition<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Le\u00a0score de Gleason<\/strong>\u00a0permet de constater le degr\u00e9 d\u2019agressivit\u00e9 du cancer de la prostate. Il s\u2019agit de l\u2019\u00e9chelle la plus couramment utilis\u00e9e. La d\u00e9termination du Gleason score est faite \u00e0 partir de l\u2019analyse de\u00a0biopsies. La\u00a0glande\u00a0prostatique contient plusieurs foyers tumoraux d\u2019\u00e9volution diff\u00e9rente et \u00e0 des stades de diff\u00e9renciations pouvant \u00eatre diff\u00e9rents (figures 3 \u2013 4 \u2013 5). Le score de Gleason est obtenu en additionnant les 2 grades histologiques allant de 1 \u00e0 5, des cancers les plus repr\u00e9sent\u00e9s.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Score de gleason : un indicateur de r\u00e9f\u00e9rence pour le cancer de la prostate<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Il est \u00e0 noter que la biopsie ne constitue que le pr\u00e9l\u00e8vement d\u2019une partie de la glande prostatique. Il s\u2019agit d\u2019un \u00e9chantillon de tissu. Cela veut dire que le r\u00e9sultat obtenu ne refl\u00e8te qu\u2019une zone de la prostate. Le Gleason score demeure cependant aujourd\u2019hui le plus puissant facteur pronostique du cancer de la prostate.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Les diff\u00e9rents types de Gleason Score<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Les grades du score de Gleason<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Le calcul du\u00a0Gleason score<\/strong> va permettre de classifier les cellules canc\u00e9reuses selon diff\u00e9rents types. Une \u00e9chelle de 1 \u00e0 5 va \u00e9valuer le degr\u00e9 d\u2019agressivit\u00e9 du cancer de la prostate.<\/p>

  • Grade 1 : les cellules semblent normales<\/li>
  • Grade 2 : le cancer appara\u00eet faible<\/li>
  • Grade 3 : stade interm\u00e9diaire de la maladie<\/li>
  • Grades 4 et 5 : les cellules ont une apparence irr\u00e9guli\u00e8re et anormale ; le cancer de la prostate est consid\u00e9r\u00e9 comme agressif.<\/li><\/ul>

    Il faut savoir que plusieurs grades peuvent coexister au sein d\u2019un m\u00eame tissu pr\u00e9lev\u00e9 lors de la biopsie.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    Le calcul du Gleason Score<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Apr\u00e8s analyse des biopsies, le Gleason score est pr\u00e9sent\u00e9 sous la forme suivante :<\/p>

    • Gleason 7 (3+4) not\u00e9 3-4<\/li>
    • Gleason 10 (5+5) not\u00e9 5-5<\/li><\/ul>

      Le premier chiffre entre parenth\u00e8se correspond au type de cellules canc\u00e9reuses le plus pr\u00e9sent dans le tissu pr\u00e9lev\u00e9. Le second chiffre de la parenth\u00e8se indique le 2\u00e8me type de cellules le plus pr\u00e9sent toujours dans le m\u00eame tissu. Ces deux chiffres correspondent aux grades \u00e9voqu\u00e9s pr\u00e9c\u00e9demment. Le Gleason score (7 et 10 dans les exemples ci-dessus) est obtenu par l\u2019addition de ces 2 chiffres. Il est compris entre 6 et 10 selon le degr\u00e9 d\u2019agressivit\u00e9 du cancer.<\/p>

      • Un score de Gleason compris entre 6 et 7 r\u00e9v\u00e8le un cancer \u00e0 risque interm\u00e9diaire.<\/li>
      • Un score de Gleason de 8 \u00e0 10 sous-entend un cancer de la prostate \u00e0 risque \u00e9lev\u00e9.<\/li><\/ul>

        \u00c0 noter : Le Gleason score ne pourra \u00eatre \u00e9valu\u00e9 apr\u00e8s certains traitements du cancer de la prostate d\u00e9j\u00e0 effectu\u00e9s. Tel est le cas de l\u2019hormonoth\u00e9rapie, la radioth\u00e9rapie externe et la curieth\u00e9rapie.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

        Gleason Score : d\u00e9finition et explications Reconnu comme facteur pronostique majeur du cancer de la prostate, le score de Gleason repr\u00e9sente aujourd\u2019hui une donn\u00e9e essentielle qu\u2019il convient de d\u00e9finir et d\u2019expliquer. Calculer le Gleason score permet au corps m\u00e9dical de mesurer l\u2019\u00e9tendue et l\u2019agressivit\u00e9 de la maladie. Le traitement du cancer de la prostate \u00e0 […]<\/p>\n","protected":false},"author":566,"featured_media":0,"parent":8932,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9053","page","type-page","status-publish","hentry"],"yoast_head":"\nGleason Score : d\u00e9finition et explications | HIFU-PROSTATE FR<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gleason Score : d\u00e9finition et explications | HIFU-PROSTATE FR\" \/>\n<meta property=\"og:description\" content=\"Gleason Score : d\u00e9finition et explications Reconnu comme facteur pronostique majeur du cancer de la prostate, le score de Gleason repr\u00e9sente aujourd\u2019hui une donn\u00e9e essentielle qu\u2019il convient de d\u00e9finir et d\u2019expliquer. 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